he frontal part of the brain handles lies.
For centuries it was thought that the frontal part of the human brain handled vision (simply because it is near the eyes). Today we know that this is false. The part that handles vision turned out to be at the rear of the brain. The front part of the brain is called the prefrontal cortex and is responsible for concocting lies. Pathological liars have more prefrontal white matter:
“Liars showed a relatively widespread increase in white matter (23-36%) in orbitofrontal, middle and inferior, but not superior, frontal gyri compared with antisocial and normal controls. This white matter increase may predispose some individuals to pathological lying.”
Localisation of increased prefrontal white matter in pathological liars. Yang Y, Raine A, Narr KL, Lencz T, LaCasse L, Colletti P, Toga AW. Br J Psychiatry. 2007 Feb;190:174-5. PubMed PMID: 17267937.
Pathological liars have more white matter at the prefrontal cortex. But 1400 years before it was discovered the Quran said that disbelievers will be dragged from their lying forehead.
[Quran 96.16] A lying sinful forehead.